Histamine is a compound involved in particular immune responses. It contributes to regulating healthy function in the GI tract, the nervous system and also plays a key role in initiating the body’s normal – and healthy – inflammatory response. An excess of histamine in your body can contribute to symptoms including flushing, runny nose, sleep difficulties and/or headaches. These irritating symptoms can be the result of slowed enzyme activity in your histamine pathway. While DAO is the main enzyme responsible for breaking down food-derived histamine in your gut, other enzymes also play crucial roles in metabolising the histamine produced in your body. When histamine is metabolised, toxic byproducts are made in the body, such as ammonia, hydrogen peroxide and acetaldehyde. These byproducts can lead to side effects and cell damage. Histamine Nutrients (Formerly Histamine Block Plus) is a blend of nutrients designed to support the breakdown of histamine via multiple enzymatic processes, as well as neutralizing the toxic byproducts that are produced, with key nutrients.

• DAO – Contains 5,000 HDU of a patented DAO, a major enzyme responsible for breaking down histamine
• Copper – A nutrient cofactor for the DAO enzyme
• SAMe – A nutrient cofactor for the HNMT enzyme, another major enzyme involved in histamine breakdown
• Alpha Keto-Glutarate – Supports the normal breakdown of ammonia, which is a toxic byproduct of histamine metabolism
• Riboflavin – A nutrient cofactor for the MAOA and MAOB enzymes, which aid in neutralizing histamine toxic byproducts
• Zinc and Vitamin B3 – Nutrient cofactors for the ALDH enzyme family, which help to break down acetaldehyde, a toxic byproduct of histamine metabolism

Please note: Histamine Digest does not reduce reactions to allergies or IgE immune-driven responses. Warning: Histamine Nutrients is not effective for symptoms of immune-related food allergies, such as peanuts, shellfish, etc., or for gluten intolerance due to sensitivity or celiac disease. Histamine Nutrients does not manage or address antibody-related or IgE-related food allergies.